Anti Portfolio
2 research articles on Anti Portfolio — drawn from 53 integrated data sources with computational validation.
Products Survive, Compounds Die: What 120 Invention Candidates Taught Us
After evaluating 120+ invention candidates across 5 rounds of a structured generate-critique-disprove-audit cycle, we found that service/API ideas survived at ~27% while compound-level ideas survived at 0%. Every compound promotion was killed as prior art. The anti-portfolio reveals systematic patterns in what kills ideas.
Why the Most Important Problems Are the Worst Investments
Three domains scored 96-97/100 on priority and produced zero surviving candidates across 120+ evaluations. PFAS-free chrome fume suppression, rare-earth element separation, and PFAS-free immersion coolants all failed because funded incumbents captured the forcing-function budget before we arrived. The counterintuitive lesson: high priority is a warning, not a green light.