OsO4

Osmium tetroxide · osmic acid

Osmium tetroxide is a stable, insulating inorganic compound widely utilized as a potent oxidizing agent and a vital staining reagent in electron microscopy.

OOs
Crystal structure of OsO4
Ground-state structure · Materials Project
Overview

About Osmium tetroxide

Osmium tetroxide is a highly distinctive inorganic oxide characterized by its insulating electronic nature and exceptional thermodynamic stability. It exists as a volatile solid that plays a critical role in specialized chemical processes due to its ability to interact selectively with organic structures.

This compound is widely valued in laboratory settings for its utility in staining biological samples and facilitating specific oxidation reactions. Its position on the convex hull underscores its structural reliability, making it a foundational reagent in advanced analytical and synthetic chemistry.

At a glance

Key Properties

Cross-validated computational properties for Osmium tetroxide, aggregated across 3 databases.

Band Gap

3.16–3.29 eV
Range across DFT structures

Energy Above Hull

0.000 eV/atom
Best (lowest) across sources

Stability

On hull (stable)
2 DFT sources

Structures

41
3 databases, 15 space groups
Synthesis

Synthesis Routes

Literature-extracted synthesis procedures targeting OsO4.

Solid State
Procedure available · ceder_solid_state
Uses

Applications

Where Osmium tetroxide is used.

Electron microscopy stainingOrganic synthesisCatalytic dihydroxylationBiological sample preparation
Reference

Frequently Asked Questions

Common questions about Osmium tetroxide, answered from cross-validated data.

What is OsO4?

Osmium tetroxide is a stable, insulating inorganic compound widely utilized as a potent oxidizing agent and a vital staining reagent in electron microscopy.

More questions
What is OsO4 used for?
Osmium tetroxide (OsO4) is used in electron microscopy staining, organic synthesis, catalytic dihydroxylation, and biological sample preparation.
What is the band gap of OsO4?
Osmium tetroxide (OsO4) has a DFT-computed band gap of 3.16–3.29 eV across 41 reported structures.
Is OsO4 a metal, semiconductor, or insulator?
With a wide band gap up to 3.29 eV it is an insulator / wide-band-gap material.
Is OsO4 thermodynamically stable?
Yes — Osmium tetroxide (OsO4) sits on the convex hull (energy above hull 0 eV/atom), i.e. on hull (stable).
How many polymorphs of OsO4 are known?
41 structures of OsO4 are reported across 3 databases, spanning 15 distinct space groups.
How is OsO4 synthesized?
Literature-reported routes for OsO4 include solid state.
What elements does OsO4 contain?
Osmium tetroxide (OsO4) contains O and Os (2 elements).
Where does the data for OsO4 come from?
OsO4 data is cross-referenced from latticegraph.
Comparison

How It Compares

As a singular, highly specialized oxide, osmium tetroxide stands apart from typical structural ceramics or semiconductors due to its unique volatility and potent reactivity. It serves as a benchmark for heavy-metal oxides used in precision staining and catalytic applications.

Data sources & attribution
  • latticegraph — Lattice Graph Materials Intelligence Platform

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