← Portfolio fitCOMPUTATIONAL MATERIALS DISCOVERYIndependent diligence

Lattice Graph × Escape Velocity (EV3)

Frontier deep-tech venture - programmable molecules & intelligence — AI-materials & critical-minerals diligence

For diligence on AI-materials and critical-minerals companies, Escape Velocity (EV3) needs an independent technical read — what's real, what's defensible, and who actually buys it.

Why nowAI-materials and critical-minerals rounds are being priced at frontier valuations faster than independent technical verification can catch up, and the one test most decks cannot survive — benchmarking a "proprietary" model against 23,196 labeled negative results that the market cannot reproduce — is available now and will widen as a competitive signal for the investors who use it first.

What our platform does for Escape Velocity (EV3)

Lattice Graph operates a computational materials-discovery platform built around a knowledge graph that spans millions of compositions, drawing on experimental literature, computed databases, and proprietary internal results. The core engine cross-validates any candidate material through multiple independent physics engines — including state-of-the-art machine-learning interatomic potentials such as MACE and CHGNet alongside density functional theory — and requires consensus across them before a result is trusted. When engines disagree, that disagreement is itself a signal: a quantitative calibration marker that tells you whether a predicted property is robust or cherry-picked from whichever method gave the most favorable number. For technical diligence in the AI-for-materials and critical-minerals space, two additional layers matter most. The first is a large-scale patent corpus — more than 300,000 materials patents — screened for whitespace, freedom-to-operate exposure, and claim density by composition family. This lets an investor ask whether a startup's claimed discovery lane is genuinely unoccupied or whether it runs straight into a thicket of prior art. The second, and harder to replicate, is a corpus of labeled negative results: 23,196 failed-experiment kill edges that document what does not work and why, accumulated from internal records that never appear in the published literature. Most AI-for-materials models have never been trained or benchmarked against a systematic failure set, because almost none exists outside of private industrial labs. Lattice Graph holds one. The platform wraps all of this in a governed, provenance-linked knowledge graph that connects composition to structure to predicted and measured properties to synthesis routes to IP status. Every claim in the graph traces back to its source, its validation history, and the disagreement profile across physics engines. For a diligence reader, that provenance chain is the difference between a result you can put in an investment memo and a result you have to trust on the founder's authority alone.

Why Lattice Graph × Escape Velocity (EV3)

Escape Velocity's thesis — that the most defensible companies of the next decade are those that design matter computationally rather than discover it by brute force — puts the firm in exactly the position where independent technical verification matters most. AI-for-materials and critical-minerals decks are now easy to construct. Every pitch claims a proprietary model, a data moat, and a credible path to a well-capitalized buyer. The problem is that almost none of those claims can be stress-tested using only publicly available tools and datasets, because the public materials corpus is overwhelmingly positive, broadly shared, and systematically blind to failure. A model trained on it will tend to over-predict success; a founder benchmarking on it will tend to over-claim defensibility. EV3 needs an independent read that does not take the target's own numbers at face value. That is the specific gap Lattice Graph fills. The platform was built to do exactly what a sophisticated technical advisor does — verify opportunity, characterize the IP landscape, and probe model quality — but with data that is not available to the market and at a speed consistent with a live deal process. The Opportunity and Buyer Intelligence engine answers the commercial question: is this discovery lane real whitespace, and does a funded buyer actually exist for the material or capability being proposed? The negatives atlas answers the technical question: does this company's model know anything the public corpus does not already give away, or does it re-predict known dead ends as successes when benchmarked against an independent failure set? Together, those two signals address the two questions a diligence committee needs answered before committing at frontier valuations. The strategic fit is also structural. EV3 invests across AI-for-science foundation models, autonomous lab platforms, generative materials companies, and the refining and separation businesses that must actually produce materials at scale. Lattice Graph's coverage spans the full stack — from discovery and prediction through IP whitespace and supply-chain concentration — so a single diligence subscription can serve the firm across its entire thesis rather than requiring a different specialist for every deal type.

Escape Velocity (EV3) business lines

  • AI-for-science & materials theses
  • Critical-minerals & energy-storage diligence
  • Technical due diligence on deep-tech rounds

Where we fit

Independent diligence in one place: the opportunity index ranks what's actually inventable; funded-buyer affinity shows who pays; and the 23,196-kill-edge negatives moat is the differentiator most AI-materials decks can't reproduce. Fast, scoped engagements (~$30–60K).

Why nowAI-materials and critical-minerals rounds are being priced at frontier valuations faster than independent technical verification can catch up, and the one test most decks cannot survive — benchmarking a "proprietary" model against 23,196 labeled negative results that the market cannot reproduce — is available now and will widen as a competitive signal for the investors who use it first.

The Lattice Graph fit for Escape Velocity (EV3)

Escape Velocity's thesis — that the most defensible companies of the next decade are those that design matter computationally rather than discover it by brute force — puts the firm in exactly the position where independent technical verification matters most. AI-for-materials and critical-minerals decks are now easy to construct. Every pitch claims a proprietary model, a data moat, and a credible path to a well-capitalized buyer. The problem is that almost none of those claims can be stress-tested using only publicly available tools and datasets, because the public materials corpus is overwhelmingly positive, broadly shared, and systematically blind to failure. A model trained on it will tend to over-predict success; a founder benchmarking on it will tend to over-claim defensibility. EV3 needs an independent read that does not take the target's own numbers at face value. That is the specific gap Lattice Graph fills. The platform was built to do exactly what a sophisticated technical advisor does — verify opportunity, characterize the IP landscape, and probe model quality — but with data that is not available to the market and at a speed consistent with a live deal process. The Opportunity and Buyer Intelligence engine answers the commercial question: is this discovery lane real whitespace, and does a funded buyer actually exist for the material or capability being proposed? The negatives atlas answers the technical question: does this company's model know anything the public corpus does not already give away, or does it re-predict known dead ends as successes when benchmarked against an independent failure set? Together, those two signals address the two questions a diligence committee needs answered before committing at frontier valuations. The strategic fit is also structural. EV3 invests across AI-for-science foundation models, autonomous lab platforms, generative materials companies, and the refining and separation businesses that must actually produce materials at scale. Lattice Graph's coverage spans the full stack — from discovery and prediction through IP whitespace and supply-chain concentration — so a single diligence subscription can serve the firm across its entire thesis rather than requiring a different specialist for every deal type.

The challenge

Name a computational feat you think we can't do.

Name a target whose central technical claim is that its model has learned something the public materials corpus does not already contain. Give us the model's predictions on a set of candidate compositions in a domain of your choosing — battery electrolytes, heterogeneous catalysts, separation membranes, or any other — and we will benchmark them against the slice of the negatives atlas covering that domain, returning a quantitative score: what fraction of the model's top-ranked candidates are known failures, how the false-positive rate compares to a naive baseline trained only on public data, and whether the model's calibration signature differs from the public-corpus baseline in any statistically meaningful way. If the model's edge is real, the test will show it. If the claimed moat is a well-narrated version of what GPT-4 already knows about chemistry, that will show too — and that is the finding that justifies the diligence fee before the check clears.

Send us a challenge →

Diligence intelligence for Escape Velocity (EV3)

Live data and API products running on our production platform — licensed to your team, with full schemas and access terms on request.

The two data products mapped to EV3 correspond to the two questions that determine whether an AI-materials investment is real. The Opportunity and Buyer Intelligence product provides the ranked index of what is genuinely inventable in a given material domain, combined with funded-buyer affinity data showing which strategics and well-capitalized industrial buyers have active programs that would pay for a specific capability or material class. In practice, this lets an EV3 analyst take a target's commercial claim — "we will sell to battery majors" or "our catalyst will be acquired by a specialty chemicals company" — and check it against who has actually funded adjacent programs and pulled on similar capabilities, rather than against a TAM slide the founder assembled. The engine also surfaces its own ranked finalists within a discovery lane, giving EV3 an independent shortlist to compare a founder's proposed roadmap against and a concrete answer to whether the lane is whitespace or already occupied. The Negatives and Eval-Data Atlas is the instrument EV3 can use to break ties on technical defensibility, and it is the harder of the two to replicate elsewhere. The corpus of 23,196 labeled failed experiments and kill edges — documented cases of what was tried and did not work, accumulated from internal records not present in the published literature — functions as a benchmark that most AI-for-materials models have never been evaluated against, because no comparable public resource exists. A diligence engagement can run a target's model or candidate list against the relevant slice of the negatives corpus, covering the specific material domain, and return a direct quantitative read: does the model re-predict known failures as successes? If a startup's claimed data moat collapses when its predictions are checked against an independent set of labeled negatives, that is precisely the finding a technical diligence read exists to surface, and it is the one test that a well-crafted founder narrative cannot preempt. The corpus can also be licensed by targets themselves for training and benchmark hardening, which is a separate signal about a company's technical seriousness.

Opportunity & Buyer Intelligence

The ranked 'what to invent / who buys it' index — opportunity scores, funded-buyer affinity, and golden finalists.

Negatives & Eval-Data Atlas

23,196 failed-experiment / kill edges plus the honest-negatives set — the labeled negative results most models never see. License for training, eval, and benchmark hardening.

In the platform for Escape Velocity (EV3)

For an EV3 analyst running a diligence pass, the most-used surfaces in the platform are the opportunity and buyer leaderboard views and the knowledge-graph explorer. The leaderboard views display the ranked discovery landscape for a given material family or application domain — showing which opportunity lanes the engine rates as genuine whitespace, which are crowded, and which have documented buyer demand — alongside the funded-buyer affinity signals that let an analyst pressure-test a go-to-market claim in minutes. These are the same signals available through the API, surfaced as a structured dashboard that drops directly into a diligence workflow without requiring a data-engineering setup. The knowledge-graph explorer gives analysts the ability to trace any specific claim — a composition, a predicted property, a stability result, a synthesis route — back to its provenance, its multi-engine validation history, and the negatives attached to that material family. Composition-intelligence reports generated through the platform produce provenance-backed, readable summaries per material that can be dropped into investment memos or shared with a partnership committee. Batch screening workflows allow an analyst to push a target's full list of claimed candidate materials through the negatives check and the trust-and-disagreement signals at once, returning a structured view of how many candidates survive contact with an independent failure corpus. These are evaluation and grounding tools sized for an investor's workflow: fast, scoped, and designed to produce a defensible technical read rather than to replicate the discovery platform internally.

How an engagement works

The natural structure for EV3 is a scoped diligence engagement rather than an asset license or co-development program. A standard pass focuses on a single target or active round: Lattice Graph runs the opportunity and buyer reality check against the claimed discovery lane, executes the negatives reproducibility test against the target's model or candidate list, and delivers an independent technical memo with findings grounded in data rather than the company's own benchmarks. Additional layers — supply-chain concentration and import-risk analysis, freedom-to-operate and patent-whitespace screening, or multi-engine trust-and-disagreement scoring on specific predicted properties — are scoped in as the thesis requires, not sold as a fixed bundle. Repeat engagements across EV3's pipeline roll into a standing diligence subscription that gives the investment team ongoing, metered access to the opportunity intelligence engine and the negatives atlas across inbound deal flow. This allows the firm to triage AI-for-materials and critical-minerals decks against a consistent independent baseline at the speed of a live process. Per the firm's lead framing, fast scoped engagements are priced in the range of thirty to sixty thousand dollars per pass, scaling with the depth of coverage and the number of material families in scope. No exclusivity or IP transfer is involved — the service is an independent technical-diligence capability plus metered data access, and findings are structured for direct use in investment committee materials.

Build the Escape Velocity (EV3) package

Scope a diligence engagement — opportunity index, buyer graph, and the negatives moat as an independent read.

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